يطبق على الأقراص والكبسولات الصلبة فقط بشرط عمل

Trend Analysis
ومراجعته من قبل المفتش

ويشترط لقبول ال 

trend analysis

 الآتي

-Process should be validated

-Trend Analysis should be controlled and repeated in case any change in

process

-Approved Raw Material supplier of proper quality

-Water used in case of wet granulation should be microbiologically controlled